SMTP replication is used only for replication between sites.
You also cannot use SMTP replication to replicate between domain controllers in the same domain—only inter-domain replication is supported over SMTP (that is, SMTP can be used only for inter-site, inter-domain replication).
SMTP replication can be used only for schema, configuration, and global catalog partial replica replication. SMTP replication observes the automatically generated replication schedule.
You also cannot use SMTP replication to replicate between domain controllers in the same domain—only inter-domain replication is supported over SMTP (that is, SMTP can be used only for inter-site, inter-domain replication).
SMTP replication can be used only for schema, configuration, and global catalog partial replica replication. SMTP replication observes the automatically generated replication schedule.